Archive for the ‘Longevity Medical Research’ Category

The Metabolic Plan

Monday, May 1st, 2006

Now at Best Seller status with 250,000 sales, “The Metabolic Plan” by healthy aging expert Stephen Cherniske is a must-read for anyone interested in a high quality of life. Cherniske has the great understanding and insight that healthy aging requires much more than a good diet and exercise. As an international expert on DHEA, he reveals his own aging process. The before and after photos strikingly demonstrate his healthy recovery and on-going improvement. Quite frankly, he shows how the metabolic approach to health improved his cholesterol levels, blood pressure, lean muscle mass, and appearance. Page 40 shows photos of him at 40 years old and 48 years old. At 48 years old, he looks much younger, healthier and more handsome. Cosmetic physicians are astounded when I share this book with them and explain that he’s had no cosmetic procedures done. With over 400 scientific references, the concepts and data presented in this book are very true and tested. Healthy aging is not just for the elite. When can use the benefits of nature to grow younger and healthier naturally. Cherniske shows us how we are all able to attain a level of health that is above average, without having to spend outrageous amounts of money on outrageous procedures. His book focuses on the wisdom of nature and science to create health.
For longevity gurus, this book serves as a strong foundation for studying anti-aging medicine. I am particularly grateful for this book as it helped me to understand important concepts in preparation for my American Board of Anti-Aging Medicine exams. The Metabolic Model of Aging is an important concept for us to understand at any age for healthy living. It is a delightful read and great reference. It lists important tests that are needed to assess longevity and health. Read this book now and get 5 more copies to give to friends- they will appreciate it!

Hot Pepper Kills Prostate Cancer

Saturday, March 18th, 2006

U.S. and Japanese researchers have announced results of a study showing that capsaicin, the chemical that makes peppers hot, can cause prostate cancer cells to kill themselves. ‘Capsaicin led 80 percent of human prostate cancer cells growing in mice to commit suicide in a process known as apoptosis, the researchers said.’ This led to tumors one fifth the size of those in untreated mice.

Celebrate Valentine’s Day with Soy Isoflavones

Monday, February 13th, 2006

Do your heart and that of your lover’s some good with including soy isoflavones in your diet. A heart-shaped block of tofu may seem like an unconventional Valentine, but it promises more health than a powdery sugar confection with the message “Be Mine” inscribed on it.

Give it to Some Bunny you love:
Soy isoflavone diets have been tested on rabbits, with positive results seen in decreasing atherosclerotic plaques. In other words, it helps decrease hardening of the arteries. To create hardening of the arteries, the research bunnies were fed casein, a protein found in cheese and some “nutritional” drinks (yikes!). But some bunnies were also fed 5mg/kg/day of isoflavones with this casein diet. The isoflavone plus casein diet bunnies showed 36% less bad cholesterol (LDL), 36% less aorta wall cholesterol, and twice as much good cholesterol (HDL) than the other group. They also had lower rates of the heat shock proteins related to atherosclerosis. (1) These isoflavones, especially genistein, has been found to protect the cells in the walls of human blood vessels at the DNA level. So the picture of vessel damage is not just about cholesterol levels and deposits. Genistein inhibits and reverses the cell death propcess that the toxic amino acid homocysteine creates. (2) It heals and protects!

Go at it like rabbits!
Nutritional supplements like soy isoflavones, vitamin E, selenium and lycopene can help protect against prostate cancer . (3) Some worry, though, that the hormonal modulation effects of soy isoflavones may interfere with fertility. A metabolite of isoflavones called Equol has the potential to decrease 5 alpha dihydrotestosterone, a very potent form of testosterone. (4) However, a study done in 2004 showed no alteration in male rabbit fertility, even at doses of 5 mg/kg/day. Some of the biochemistry in the rabbit semen even improved, like HDL levels.(5)
So when you want to make your true love a heart-healthy, sex healthy treat this Valentine’s Day, include soy isoflavones like that in tofu, on your holiday menu! Happy Valentine’s Day!

References:
1 Rosier Olimpio Pereira I Saes Parra Abdall D. Soy isoflavones reduce heat shock proteins in experimental atherosclerosis. Eur J Nutr, 2005 Nov 24
2 Fuchs D, et al. Genistein blocks homocysteine-induced alterations in the proteome of human endothelial cells. Proteomics. 2005 Jul;5(11):2808-18
3 Kucuk O. Chemoprevention of prostate cancer. Cancer Metastis Rev2002;21(2):111-24.
4 Lephart ED, et al. ILAR 2004; 45(4):443-54
5 Yousef MI, et al. J Environ Sci Health B. 2004;39(5-6):819-33

Natalie Kather, MD

Bioenergetic Substances: Do you get enough in your diet?

Saturday, January 28th, 2006

Bioenergetic substances are chemicals that help your cells’ energy production improve in a healthy, non-stressful way. Stimulants, like caffeine and nicotine stress the adrenals and central nervous system, but bioenergetics just help the body’s energy system work better. Inside each cell are many, many power houses called mitochondria. These little factories incinerate fatty acids and turn them into ATP, the currency of biologic energy. Bioenergetics benefit this process by either improving the mechanics of the process, or by providing anti-oxidant protection to the mitochondrial structure.
For example, L-carnitine acts like a worker that stokes the fire by putting or pulling fatty acids into the mitochondrial incinerator. Co Q10 and alpha lipoic acid are important anti-oxidants that protect the incinerator structure from the “rusting” that occurs with this highly oxidative process. The fire of this process is the Kreb’s Cycle. Components of this cycle and processes feeding into it also act as bioenergetics, including magnesium aspartate, potassium aspartate, alpha ketoglutarate, and pyridoxal-5-phosphate (the MOST bioavailable form of vitamin B6).
It’s best to combine the substances that improve the mechanics with those that serve as anti-oxidants so that these energy factories run optimally and also stay in good shape . In other words, protect the Kreb’s cycle with anti-oxidants. So if you’re feeling sluggish, don’t reach for that cafeinated drink, reach for a great bioenergetic supplement instead! Your body will love you for it, and you will have better energy all around in the long run.
This is Dr. Natalie’s personal list of bioenergetics and anti-oxidants that she takes to optimize her energy and health:
acetyl L-carnitine (it helps brain function too! She gets this in her Oasis Life Sciences Ageless Prime.)
pyridoxal-5-phosphate (Oasis Life Sciences Ageless Prime and AgelessXtra)
alpha lipoic acid (Oasis Life Sciences AgelessXtra)
Selenium (Vitaline formulas)
Zinc (Solaray)
Vitamin E ( mixed forms are best, not just alpha tocopherol. Gamma tocopherol is a better choice. Did you know there are at least 8 different forms of vitamin E, including tocopherols and tocotrienols?)
Vitamin C
Magnesium malate
Anti-oxidants from fruits and vegetables (Oasis Life Sciences Metagreens, Metaberry, Aloe Gold and AgelessXtra)
N-acetyl cysteine (detoxifies the brain and liver! Oasis Life Sciences Ageless Prime)
CoQ10, EPA, DHA (purified fish oil Metapower from Oasis Lifsciences)
Bio-identical hormone replenishment (Yep! They are bioenergetics too! Just remember to also include the above substances also because with hormones, the speeds of processes are increased. So what little supply of vitamins, minerals, anti-oxidants, and etc. are there, will get used up even faster.)
Vitamin D (cholecalciferol. It’s actually an anabolic steroid!)
Thyroid hormone
Progesterone
Testosterone
Dehydroepiandrosterone (DHEA)
7-keto DHEA
Pregnenolone
Melatonin

Bioenergetics are awesome substances, helping the body to function better and become healthier! Include them in your diet everyday!
Best Wishes in Health,
Dr. Natalie

Book Review: The Edge Effect

Monday, January 9th, 2006

The Edge Effect is a helpful healthy aging guide by Dr. Eric Braverman, a specialist in “neuropause,” or the slowing of the brain’s function. His book helps people identify their strengths and weaknesses in the four main neurotransmitter systems: serotonin, gama amino butyric acid, dopamine, and acetylcholine. It is a chemical exploration into one’s mind. He offers useful hormone, amino acid, and dietary recommendations to help optimize each of these neurotransmitters and bring balance to the brain.

I encourage anyone who wants to improve their “edge” to read this book. It is easy to understand, and can provide a path to a better functioning brain!

Natalie Kather, MD
diplomate of the American Board of Anti-Aging Medicine
and diplomate of the Amercian Board of Family Medicine

Cancer fighting agent found only in hops

Monday, November 28th, 2005

A Healthy Beer is already being developed, due to an important cancer fighting agent found only in hops.

“waist-to-hip ratio” is a better predictor of heart attacks

Saturday, November 12th, 2005

McMaster University in Hamilton, Ontario recently found “waist-to-hip ratio” is a better predictor of heart attacks than BMI or weight. More here

Moderate Alcohol Use May Thin Blood

Saturday, October 22nd, 2005

CNN has a story running on the netscape portal about how
Moderate Alcohol Use May Thin Blood.

Scientists may have found an antiaging hormone in mice

Monday, September 5th, 2005

The hormone is a protein naturally made by the mice. In lab tests, researchers found that mice that make a lot of that protein lived about 20% longer than normal mice.

More information is available on webmd.com

Hugging helps you live longer

Tuesday, August 9th, 2005

Scientists have confirmed the wisdom of mothers down the ages – a real hug does you good:

http://news.independent.co.uk/world/science_technology/article304281.ece